熔点 | 247-249°C |
敏感性 | 对热敏感 |
溶解性 | Soluble in Chloroform and Methanol |
存贮条件 | 储存温度-20°C |
应用 | A potent, non-selective inhibitor of HIV-1 reverse transcriptase. |
产品介绍 | Nevirapine 是一种非核苷逆转录酶抑制剂(NNRTI),用于治疗HIV-1感染和AIDS。 |
备注 | Nevirapine(Viramune) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. |
生化机理 | Nevirapine is a potent (IC50 = 84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase (HIV-1 RT). |
别名 | 奈韦拉平; 11-环丙基-5,11-二羟基-4-甲基-6H-二吡啶并[3,2-b:2',3'-e][1,4]二氮杂唑-6-酮 ;Viramune; BI-RG 587; NSC 641530; NVP;11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one |