产品描述
| 熔点 | 165-167 °C |
| 溶解性 | Soluble in water (0.5 mg/ml at 25 °C), ethanol (~5 mg/ml), DMSO (20 mg/ml), DMF (20 mg/ml), and methanol. |
| 存贮条件 | 储存温度-20°C |
| 应用 | An inhibitor of Cox-1, Cox-2, and 5-lipoxygenase. |
| 产品介绍 | Licofelone是COX/LOX的双重抑制剂，用于治疗骨关节炎。 |
| 备注 | Licofelone is a dual COX/LOX inhibitor being considered as a treatment for osteoarthritis. |
| 生化机理 | Licofelone is an anti-inflammatory and dual inhibitor of cyclooxygenase and 5-LO(5-lipoxygenase). Licofelone inhibits both Cox-1 and Cox-2. |
| 别名 | 利克飞龙; 2-[2-(4-氯苯基)-6,6-二甲基-1-苯基-5,7-二氢吡咯烷嗪-3-基]乙酸;ML-3000;ML-3000;2-[2-(4-Chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid; [2,2-Dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]acetic acid |
