产品描述
| 溶解性 | Soluble in water (4 mg/mL), DMSO (>5 mg/mL), acetone, acetonitrile, chloroform, and methanol. |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | An ST (SERT) inhibitor. |
| 产品介绍 | Fluoxetine HCl是一种抗抑郁剂，选择性抑制5-羟色胺再摄取。 |
| 备注 | Sold under license from Eli Lilly and Company.Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months. |
| 生化机理 | Fluoxetine is an ST (5-hydroxytryptamine/serotonin/5-HT reuptake) inhibitor. This is a racemic mixture and both R and S enantiomers which are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Additionally, Fluoxetine is also noted to increase extracellular levels of 5-HT in several areas of the rat brain as a result of reuptake inhibition. This increase in availability of 5-HT is reported to lead to a decrease in synthesis and turnover of 5-HT. |
| 别名 | 氟西汀 盐酸盐;(±)-N-甲基-γ-[4-(三氟甲基)苯氧基]苯基丙胺 盐酸盐;LY-110,140 盐酸盐;盐酸氟西汀;(±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride;LY-110,140 hydrochloride;N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine Hydrochloride;LY110140; LY 110140; LY-110140 |
