溶解性 |
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应用 | A HDAC6 and HDAC10 inhibitor. |
产品介绍 | Bufexamac是一种环氧酶抑制剂,靶点是IFN-α, EC50 为8.9 μM。 |
备注 | Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM. |
生化机理 | Bufexamac is a specific inhibitor of HDAC6 and HDAC10. Treatment of peripheral blood mononuclear cells with bufexamac inhibits the secretion of IFN-α. Bufexamac is a frequent and relevant contact sensitizer. |
别名 | 对丁氧苯乙酰氧肟酸;丁苯羟酸;2-(4-丁氧苯基)醋羟胺酸;4-丁氧基-N-羟基苯乙酰胺;2-(p-Butoxyphenyl)acetohydroxamic acid;2-(4-Butoxyphenyl)acetohydroxamic Acid;2-(4-Butoxyphenyl)-N-hydroxyacetamide |