产品描述
| 熔点 | 135°C |
| 溶解性 | Soluble in water (81 mg/ml at 25 °C), DMSO (50 mg/ml at 25 °C), ethanol (81 mg/ml at 25 °C), and ether (very slightly). |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | An antagonist of the mAChR. |
| 产品介绍 | Benztropine mesylate是一种多巴胺转运蛋白抑制剂，IC50为118 nM。 |
| 备注 | Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM. |
| 生化机理 | Benztropine mesylate is a derivative of Atropine and an antagonist of the mAChR (muscarinic acetylcholine receptor). This compound demonstrates anti-muscarinic effects comparable to Atropine, and also demonstrates competitive anti-nicotinic action at the nAChR (nicotinic acetylcholine receptor) unobserved with Atropine |
| 别名 | 苯托品 甲磺酸酯;苯扎托品 甲磺酸酯;甲磺酸苯扎托品;Benztropine hydrobromidum;Benztropine methanesulfonate;Benzatropine mesylate;Endo-3-(diphenylmethoxy)-8-methyl-8-azoniabicyclo[3.2.1]octane methanesulphonate |
