熔点 | 135-137 °C |
旋光率 | -4° (C=1,MeOH) |
敏感性 | 对热敏感 |
溶解性 | Soluble in water (<1 mg/ml), DMSO (58 mg/ml at 25 °C), methanol, and ethanol (58 mg/ml). |
存贮条件 | 储存温度 2-8°C |
应用 | A serotonin 5HTID-receptor agonist. |
产品介绍 | Zolmitriptan 是一种选择性5-羟色胺受体激动剂。 |
备注 | Zolmitriptan(Zomig) is a selective serotonin receptor agonist. |
生化机理 | Zolmitriptan is a selective serotonin receptor agonist of the 5HT1B and 5HT1D subtypes, both centrally and peripherally. It has been used clinically for the acute treatment of migraine attacks with or without aura and cluster headaches. |
别名 | 佐米曲坦;佐米曲普坦;(S)-4-[[3-[2-(二甲氨基)乙基]-1H-吲哚-5-基]甲基]-2-恶唑烷酮;(4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone; (S)-4-((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)-2-oxazolidinone ;BW-311C90; Zomig; 311C90 |