产品描述
| 溶解性 | Soluble in methanol, water (4 mg/ml at 25 °C), ethanol (1 mg/ml at 25 °C), and DMSO (1 mg/ml at 25 °C) |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | A platelet aggregation inhibitor |
| 产品介绍 | Ticlopidine HCl是一种P2受体抑制剂，可以抑制ADP诱导的血小板聚集，IC50约为2μM. |
| 备注 | Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM. |
| 生化机理 | Ticlopidine hydrochloride is a platelet aggregation inhibitor capable of inducing apoptosis in various cancer cell lines by antagonizing the P2Y12 receptor, which is responsible for initiating the signal transduction that causes platelets to aggregate. |
| 别名 | 盐酸噻氯匹定;5-(邻氯苄基)-4,5,6,7-四氢噻吩并(3,2-c)吡啶;噻氯匹定盐酸盐;5-(2-氯苯甲基)-4,5,6,7-四氢噻吩并[3,2-c]吡啶盐酸盐;噻氯匹定盐酸盐;Ticlopidine hydrochloride;5-(o-Chlorobenzyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine;5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine Hydrochloride |
