产品描述
| 熔点 | 136-138 °C |
| 溶解性 | Soluble in DMSO (59 mg/ml), methanol, and ethanol (<1 mg/ml). Insoluble in water. |
| 存贮条件 | 储存温度-20°C |
| 应用 | A Cox-2 selective inhibitor and NSAID. |
| 产品介绍 | Lumiracoxib是一种新型，选择性的COX-2抑制剂，IC50和Ki分别为0.14 μM和0.06 μM，比作用于COX-1选择性高515倍。 |
| 备注 | Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4. |
| 生化机理 | Lumaricoxib is a Cox-2 selective inhibitor NSAID member of the arylalkanoic acid family of NSAIDs. Lumaricoxib binds to a separate site than that of other Cox-2 inhibitors. |
| 别名 | 罗美昔布;鲁米昔布;2-[(2- 氯-6-氟苯基)氨基」-5-甲基苯乙酸;2-[2-[(2-Chloro-6-fluorophenyl)amino]-5-methylphenyl]acetic acid |
