溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
产品介绍 | MLN120B是IKKβ抑制剂。 |
生化机理 | ML120B is a potent inhibitor of IKK-2 (IC50 = 60 nM). ML120B is orally bioavailable, and inhibits paw swelling, bone and cartilage degradation, and weight loss in rat adjuvant-induced arthritis. |
别名 | ML120B;MLN 120B;MLN-120B;N-(6-氯-7-甲氧基-9H-吡啶并[3,4-b]吲哚-8-基)-2-甲基-3-吡啶甲酰胺;ML120B;MLN 120B;MLN-120B;N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methyl-3-pyridinecarboxamide |