溶解性 | DMSO ≥200mg/mL Water ≥1.2mg/mL Ethanol ≥200mg/mL |
存贮条件 | 储存温度-20°C |
应用 | A potent inhibitor of FRAP (mTOR) kinase activity |
产品介绍 | Temsirolimus (CCI-779) 抑制mTOR激酶活性 IC50值为1.76 ± 0.15 μM。 |
备注 | Temsirolimus (CCI-779) is a specific mTOR inhibitor with IC50 of 1.76 μM. |
生化机理 | Temsirolimus (also known as CCI-779) is a recently developed mTOR inhibitor. with improved aqueous solubility and more favorable pharmaceutical properties compared with the parent compound rapamycin. |
别名 | 西罗莫司脂化物; 雷帕霉素 42-[3-羟基-2-(羟甲基)-2-甲基丙酸酯;Torisel;CCI-779;CCI 779;CCI779;Rapamycin 42-(2,2-bis(hydroxymethyl)propionate);Rapamycin 42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate |