溶解性 |
|
存贮条件 | 储存温度-20°C |
应用 | A PI3K inhibitor |
产品介绍 | PIK-293 is a PI3K inhibitor, mostly for PI3Kδ with IC50 of 0.24 μM, 500-, 100- and 50-fold less potent to PI3Kα/β/γ, respectively. |
生化机理 | PIK-293 is a PI3-K inhibitor. PIK-293 inhibits the p110α, p110β, p110δ, and p110γ with IC50 of 100 μM, 25 μM, 0.24 μM,and 10 &kkkmu;M. PIK-293 is the parent compound of PIK-294. |
别名 | 2-[(4-氨基-1H-吡唑并[3,4-d]嘧啶-1-基)甲基]-5-甲基-3-(2-甲基苯基)-4(3H)-喹唑啉酮;2-[(4-Amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone; 2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one |