产品描述
| 溶解性 |
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| 存贮条件 | 储存温度-20°C |
| 产品介绍 | Saxagliptin(BMS477118)是选择性可逆的DPP4抑制剂，IC50和Ki分别为26 nM和1.3 nM。 |
| 备注 | Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM. |
| 生化机理 |
Saxagliptin is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. |
| 别名 | 沙克列汀；沙格列汀；(1S,3S,5S)-2-[(2S)-2-氨基-2-(3-羟基三环[3.3.1.1(3,7)]癸烷-1-基)乙酰基]-2-氮杂双环[3.1.0]己烷-3-腈；;BMS-477118；Onglyza；BMS 477118；BMS477118； |
