产品描述
| 溶解性 | Soluble in methanol, water (partly), ethanol (~5 mg/ml), DMF (~15 mg/ml), and DMSO (100 mg/mL at 25 °C). |
| 存贮条件 | 储存温度 2-8°C |
| 产品介绍 | Ritonavir是一种HIV蛋白酶抑制剂，用于治疗HIV感染和AIDS。 |
| 备注 | Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS. |
| 生化机理 | Ritonavir is an inhibitor of HIV-1 protease used to treat HIV infection and AIDS. Currently rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors. More specifically, ritonavir is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, CYP3A4 (cytochrome P450-3A4). |
| 别名 | 利托那韦; N-[(2S,3S,5R)-3-羟基-5-[[(2S)-3-甲基-2-[[甲基-[(2-异丙基-1,3-噻唑-4-基)甲基]氨基甲酰]氨基]丁酰]氨基]-1,6-二苯基-己-2-基]氨基甲酸 5-噻唑基甲基酯;A 84538; ABT 538; Abbott 84538; NSC 693184; Norvir; RTV;Thiazol-5-ylmethyl [(1S,2S,4S)-1-benzyl-2-hydroxy-4- [[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol- 4-yl]methyl]carbamoyl]amino]butanoyl]amino]-5- phenylpentyl]carbamate. |
