产品描述
| 溶解性 | DMSO 52 mg/mL Water <1 mg/mL Ethanol 52 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | NSC 405020是一种MT1-MMP抑制剂，直接与MT1-MMP的PEX区域相互作用，影响PEX二聚体化，但不影响MT1-MMP的催化活性。 |
| 备注 | NSC 405020 is a noncatalytic inhibitor of MT1-MMP, directly interacts with PEX domain of MT1-MMP, affects PEX homodimerization but not catalytic activity of MT1-MMP. |
| 生化机理 | NSC405020 is a PEX inhibitor targeting the PEX domain of MT1-MMP that repressed tumor growth and caused a fibrotic DPEX-like tumor phenotype in vivo. NSC405020 does not inhibit the catalytic activity of MMP-2. |
| 别名 | 3,4-二氯-N-(1-甲基丁基)-苯甲酰胺;NSC405020; NSC-405020;3,4-Dichloro-N-(1-methylbutyl)-benzamide 3,4-Dichloro-N-(pentan-2-yl)benzamide ;NSC 405020;NSC-405020 |
