产品描述
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
| 备注 | OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM). |
| 生化机理 |
OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. |
| 别名 | 2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride;2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride |
