产品描述
| 溶解性 |
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| 存贮条件 | 储存温度-20°C |
| 应用 | A multi-targeted tyrosine kinase inhibitor of PDGF and c-Kit。 |
| 产品介绍 | Amuvatinib (MP-470)是多靶点抑制剂，对c-Kit(D816H)，PDGFRα(V561D)和FLT3(D835Y)的IC50分别为10 nM，40 nM和81 nM。 |
| 生化机理 | Amuvatinib is a potent and multi-targeted tyrosine kinase inhibitor that inhibits c-Kit and PDGFα and has been shown to induce apoptosis. |
| 别名 | MP-470; MP 470; MP470; HPK 56; N-(1,3-苯并二氧戊环-5-基甲基)-4-苯并呋喃并[3,2-d]嘧啶-4-基-1-哌嗪硫代甲酰胺;Amuvatinib；MP-470; MP 470; MP470; HPK 56；N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide |
