溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
产品介绍 | ASP3026是高活性ALK抑制剂,IC50为3.5 nM。 |
生化机理 | ASP3026 shows more selective ALK inhibition in a Tyr-kinase panel than PF02341066. ASP3026 inhibits the growth of NCI-H2228, a human NSCLC tumor cell line endogenously expressing EML4-ALK variant 3, with an IC50 value of 64.8 nM。 |
别名 | ASP 3026;ASP-3026; N2-(2-甲氧基-4-(4-(4-甲基-1-哌嗪基)-1-哌啶基)苯基)-N4-(2-((1-甲基乙基)磺酰基)苯基)-1,3,5-三嗪-2,4-二胺;;ASP 3026;ASP-3026;n2-(2-methoxy-4-(4-(4-methyl-1-piperazinyl)-1-piperidinyl)phenyl)-n4-(2-((1-methylethyl)sulfonyl)phenyl)-1,3,5-triazine-2,4-diamine |