产品描述
| 敏感性 | 对热敏感 |
| 溶解性 | Soluble in DMSO at 50mg/ml or methanol at 25mg/mlSoluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water. |
| 存贮条件 | 储存温度 -20°C,充氩保存 |
| 应用 | Rapamycin 是一种特异性的 mTOR 抑制剂，IC50 为 0.1 nM。 |
| 生化机理 | A macrocyclic triene antibiotic that binds to and inhibits the molecular target of rapamycin (mTOR). It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). Rapamycin is a potent immunosuppressant and has anticancer activity. |
| 别名 | 西罗莫司;AY 22989;雷帕霉素Sirolimus;23,27-?Epoxy-?3H-?pyrido[2,1-?c]?[1,4]?oxaazacyclohentriacontine;AY 22989 |
