产品描述
| 敏感性 | 对光线敏感 |
| 溶解性 | Soluble in DMSO (25 mg/ml), and methanol (5 mg/ml). |
| 存贮条件 | 储存温度 -20°C |
| 应用 |
Selectively inhibits arachidonoyl-CoA synthetase in intact cells. Inhibits the nonspecific acyl-CoA synthetase in cell sonicates IC50=3.6-8.7 μM1–3. Inhibits neutrophil functions |
| 产品介绍 | Triacsin C, an analog of polyunsaturated fatty acid. A potent vasodilator. |
| 生化机理 | Triacsin C is a potent inhibitor of long-chain fatty acyl CoA synthetase. It blocks β-cell apoptosis, induced by fatty acids (lipoapoptosis) in a rat model of obesity. In addition, it blocks the de novo synthesis of triglycerides, diglycerides, and cholesterol esters, thus interfering with lipid metabolism. |
| 别名 | ;2E, 4E, 7E-Undecatriene-1-triazene; 2,4,7-Undecatrienal nitrosohydrazone WS1228A |
