产品描述
| 敏感性 | 对光敏感 |
| 溶解性 | Cerulenin is soluble in DMSO, Methanol, Ethanol, Dichloromethane, Acetone, Benzene and most common solvents. Concentrations up to 20 mg/ml can be achieved. Slightly soluble in H2O. Concentrations up to 0.2 mg/ml are achievable. Not soluble in Petrol Ether |
| 存贮条件 | 储存温度-20°C,充氩储存 |
| 密度 | 1.1340 |
| 应用 | An inhibitor fatty acid and sterol biosynthesis |
| 产品介绍 | Cerulenin has broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to β-keto-acyl-ACP .synthase blocking the interaction of malonyl CoA. Cerulenin also an inhibits bacterial fatty acid synthesis, acting on the FabH, FabB and FabF condensation enzymes. Cerulenin stimulates fatty acid oxidation and inhibits HMG-CoA synthetase activity. |
| 生化机理 | Cerulenin, an antibiotic and antifungal, is an inhibitor of fatty acid biosynthesis; in vitro inhibition of HIV-1 proteinase. |
| 别名 | 浅蓝菌素;(2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide;Helicocerin |
