溶解性 | 1 mg/mL (in 1% TFA in H20) |
存贮条件 | 储存温度:-20°C |
应用 | Bactenecin′s activity has been studied as a cyclic molecule as well as in a linear form.It was used to study the functional role of Trk1p in the mechanism of other antifungal peptides. It has been used to study chemokine and cytokine production, alteration of gene expression in host cells, and inhibition of proinflammatory responses of host cells to bacterial components. |
产品介绍 | 氨基酸序列 Arg-Leu-Cys-Arg-Ile-Val-Val-Ile-Arg-Val-Cys-Arg-OH (Disulfide bridge: 3-11) |
备注 | 肽类抗生素,最初从牛中性粒细胞颗粒分离出来的 |
生化机理 | Bactenecin is a 12-amino acid cationic antimicrobial peptide from bovine neutrophils. It strongly binds to LPS and perturbs the structure, fluidity and permeability of the inner membrane. This results in the leakage of cytosol and subsequent death of the bacteria. |
别名 | 牛〔白細胞〕抗菌肽; |