敏感性 | 易吸潮 |
溶解性 | Soluble in water. Slightly soluble in methanol, ethanol and dimethylsulfoxide. |
存贮条件 | 储存温度2-8℃;充氩保存 |
应用 | 为窄谱抗生素,仅对革兰阳性菌有效,如溶血性链球菌、肺炎球菌、淋球菌及肠球菌等均属敏感,对耐药金葡菌本品尤为敏感。其作用机制是抑制细菌细胞壁的合成,它主要和细菌细胞壁结合,而使某些氨基酸不能进入细胞壁的糖肽中。 |
产品介绍 | 溶于水。 |
生化机理 | Vancomycin is a glycopeptide antibiotic that blocks bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. It is effective against Gram-positive bacteria. Vancomycin also alters bacterial-cell-membrane permeability and RNA synthesis. |
别名 | 万古霉素 ;Vancomycin hydrochloride |