产品描述
| 熔点 | 83°C-87°C |
| 溶解性 | Soluble in water (50 mg/ml), DMSO (>10 mg/ml), chloroform (10 mg/ml), ethyl acetate (>10 mg/ml), and acetonitrile (>10 mg/ml) |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | Penicillic acid is used to study FasL-induced apoptosis and cell viability in Burkitt′s lymphoma Raji cells，and is used to study bacterial bioluminescence bioassays and genotoxicity of hepatocytes. |
| 产品介绍 | Penicillic acid: a Mycotoxin that induces DNA single-strand breaks |
| 生化机理 | Penicillic acid is a mycotoxin isolated from various strains of Penicillium and Aspergillus fungi that demonstrates mutagenic and cytotoxic effects. This compound is demonstrated to induce single-strand DNA breaks and to inhibit DNA synthesis in CHO cells. Penicillic acid is also reported to irreversibly inactivate GMD (GDP-mannose dehydrogenase), interrupting the committed step in alginate biosynthesis. Penicillic acid is an inhibitor of ADH/AKR1A1 and LDH. |
| 别名 | PA;3-Methoxy-5-methyl-4-oxo-2,5-hexadienoic acid;PA |
