产品描述
| 熔点 | 178-184°C |
| 存贮条件 | 储存温度 2-8℃ |
| 应用 |
抑制微导管（microtubule）组装；抗肿瘤。
临床上用于急性单核细胞型和急性粒单核细胞型白血病，急性粒细胞白血病，慢性嗜酸粒细胞型白血病，小细胞肺癌，非何杰金氏恶性淋巴瘤、 睾丸癌等。 |
| 产品介绍 | 无臭无味，不溶于水、 易溶于水、易溶于氯仿、 甲醇和丙酮。 |
| 生化机理 |
Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use. |
| 别名 | 鬼臼毒素;盾叶鬼臼，5R,5aR,8aR,9R)-5R-5,8,8a,9-四氢-9-羟-5-(3,4,5-三甲氧苯基)呋喃(3',4':6,7)萘并-[2,3-d]-1,3-间二氧杂环烯-6(5aH)-酮Podophyllinic acid lactone |
