产品描述
| 熔点 | 84-100°C |
| 溶解性 | Soluble in EtOH, acetone (50 mg/ml), DMSO (300 mg/ml), ethanol, and methanol. Insoluble in water |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | A specific inhibitor of the mitochondrial ATP-synthase. |
| 产品介绍 | Oligomycin is a macrolide that acts as a specific inhibitor of the mitochondrial ATP-synthase and blocks oxidative phosphorylation. The compound is a mixture of isomers A ,B , and C .Cancer cell studies show that Oligomycin does not activate the hypoxia-induced factor, however, it enhances the bioenergetic adaptation of heterogeneous bioenergetically organized cells. Oligomycin has been shown to decreased the cyclin D1 protein expression levels |
| 备注 | 该产品为A, B 和 C的混合物 |
| 生化机理 | Macrolide antibiotic; inhibits mitochondrial ATPase and phosphoryl group transfer. |
| 别名 | Oligomycin;Oligomycin a, b, c mixture |
