熔点 | 227-228°C |
溶解性 | Soluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water |
存贮条件 | 2-8℃ |
密度 | 1.3440 |
应用 |
氟哌酸昌日本杏林公司1978年开发的第三代喹诺酮类抗菌剂。具有抗菌谱广、抗菌力强的特点。 Norfloxacin may be used as a standard in the determination of norfloxacin in human serum samples using fluorometric spectrophotometry. Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
产品介绍 | 类白色至淡黄色结晶性粉末。易溶于酸,碱溶液,极微溶于水和醇。无臭、味微苦。 熔点:227-228℃ Chemical structure: fluoroquinolone Norfloxacin is a broad spectrum antibiotic, which is used against a wide variety of gram positive and gram negative bacteria. |
生化机理 | Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase). Mode of action: inhibits bacterial DNA replication Antimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria |
别名 | 诺氟沙星;氟哌酸,1-乙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-3-喹啉羧酸;1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid |