产品描述
| 敏感性 | 对热和空气和光线敏感 |
| 溶解性 | Soluble in water (50 mg/ml).10 mM NaOH: soluble 50 mg/mL, clear |
| 存贮条件 | 储存温度-20℃；充氩保存 |
| 密度 | 2.2800 |
| 应用 | 通常作为电子供体，是很多氧化还原酶(包括一氧化氮合成酶)的辅酶(cofactor)。 |
| 产品介绍 | β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP). |
| 生化机理 | NADPH, Tetrasodium Salt ia a ubiquitous cofactor and biological reducing agent that acts as an electron donor in many biological reactions. It is generated by reduction of the electron acceptor NADP+, and is very similar to another cofactor, NADH, which lacks a phosphate group at position 2’ of the ribose moiety on the adenine half of the dinucleotide. This compound is involved in many pertinent biochemical pathways, including: formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin, and formation of free radicals in immune cells which are used to destroy pathogens - aka the respiratory burst. |
| 别名 | 还原型辅酶Ⅱ四钠盐;β-烟碱腺嘌呤二核苷磷酸盐四钠盐,还原型;β-三磷酸吡啶二核苷酸四钠盐;2′-NADPH 水合物;二氢烟酰胺腺嘌呤二核苷酸磷酸 四钠盐;还原型三磷酸吡啶核苷酸 四钠盐;β-NADPH;β-NADPH; 2′-NADPH hydrate; Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt; NADPH Na4; TPNH2 Na4; Triphosphopyridine nucleotide reduced tetrasodium salt; β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate; NADPH tetrasodium salt; beta-Nicotinamide adenine dinucleotide phosphate (reduced form, beta-NADPH); Coenzyme II Tetrasodium Salt reduced form;β-NADPH Tetrasodium Salt reduced form; |
