敏感性 | 对光和热敏感 |
存贮条件 | 储存温度-20°C |
应用 | decarboxylation mechanisms in biological systems,and to investigate radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases. |
生化机理 | Thiamine pyrophosphate is a coenzyme of transketolase that catalyzes the cleavage of ribulose-5-phosphate; thereby forming D-glyceraldehyde-3-phosph?ate. This reaction requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. The enzyme is also capable of decarboxylating hydroxypyruvate in the presence of an ′acceptor aldehyde′. |
别名 | 羧化辅酶(氯化);二磷酸硫胺;氯化维生素B1磷酸酯;3-[(4-氨基-2-甲基-5-嘧啶基)甲基]-5-[2-[[羟基-(磷酸基氧代)磷酰]氧]乙基]-4-甲基噻唑氯化物;硫胺素二磷酸盐;Aneurinepyrophosphoric acid; Cocarboxylase; Thiamine pyrophosphate chloride; Vitamin B1 Pyrophosphoric Acid Ester Chloride; |