产品描述
| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in water (116 mg/mL) at 25 °C, DMSO (116 mg/mL) at 25 °C, ethanol (3 mg/mL) at 25 °C, acetone, and methanol. |
| 存贮条件 | 储存温度-20°C |
| 应用 | 表柔比星是一种细胞渗透性的蒽环类抗肿瘤抗生素。它是多柔比星表现出降低心脏毒性的立体异构体（4'-表异构体）。它常用来抑制拓扑异构酶II和DNA解旋酶的活性。表柔比星是用来研究转移性乳腺癌和心脏毒性。 |
| 产品介绍 | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia |
| 生化机理 | 可渗透细胞的蒽环类抗肿瘤抗生素。抗肿瘤药。表柔比星的立体异构体表现出降低心脏毒性。其抗癌行动是由靶位点拓扑异构酶II介导的。表柔比星具抗有丝分裂和细胞毒性。它抑制核酸和蛋白质的合成。表柔比星通过与DNA形成复合物和并嵌入碱基对之间，通过使DNA拓扑异构酶Ⅱ复合稳定而抑制拓扑异构酶II活性。它抑制DNA螺旋酶的活性。 |
| 别名 | 盐酸表阿霉素;4′-Epidoxorubicin hydrochloride, Epidoxorubicin hydrochloride |
