熔点 | 199 °C |
敏感性 | 对热敏感 |
溶解性 | Soluble in methanol, DMSO, water (slightly), DMF, and chloroform |
存贮条件 | 储存温度 -20°C |
应用 | 5-乙炔基-2′-脱氧尿苷(EdU)是一种胸苷类似物,可掺入到新合成的复制DNA中,以检测细胞增殖。它具有炔烃连接基团,可通过高效的点击化学反应与含叠氮基的荧光探针连接。EdU核苷可以掺入到培养物或动物的细胞DNA中,并且无明显的毒性。该测定是比抗BrdU测定更简单的细胞增殖测定方法。 |
产品介绍 | 5-Ethynyl-2'-deoxyuridine(EdU) is an extensively used nucleoside analog used as a probe for DNA synthesis. 5-Ethynyl-2’-deoxyuridine is known as an toxic anti-metabolite, which potentially causes DNA instabiliy, necrosis and cell-cycle arrest, therefore it is often used for short-term DNA synthesis in tissue culture and living organisms where prolonged cell survival is not required. |
别名 | 5-乙炔基-2‘-去氧尿苷;5-EdU; 2'-Deoxy-5-ethynyluridine |