Calcein, AM

Calcein, AM

产品参数

货号 规格 操作
C131116-5mg 咨询
C131116-1mg 咨询
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服务地域:全国

属性:产地:上海; 品牌:阿拉丁 ;货期:现货

上海阿拉丁生化科技股份有限公司

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属性

敏感性 对光敏感
存贮条件 储存温度 -20°C

描述

应用 A non-fluorescent, membrane permeable probe that can be hydrolyzed to a fluorescent molecule
产品介绍 Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein , which is an extremely fluorescent and negatively charged molecule. The probe can be used to stain living cells and has been observed to fluoresce bright green in cytoplasmic Schwann cells. Calcein-AM has been reported to be a neutral substrate for Mdr (P-glycoprotein (Pgp) and multidrug resistance protein (MRP)) and has been used in flow cytometry studies to analyze the function of P-gp and MRP. Studies suggest that Calcein-AM can be used to detect MDR mediated resistance and to be transported by PGP from the plasma membrane. Mitochondrial permeability research has utilized Calcein as a cytosolic fluorophore. Has been used as a cytosolic fluorophore in mitochondrial permeability studies to image pore transition.
别名 CAL-AM;CalceinCalcein O,O′-diacetate tetrakis(acetoxymethyl) ester;Calcein acetoxymethyl ester;CAL-AM
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