熔点 | 203-205°C |
旋光率 | 25 ° (C=5, 6mol/L HCl) |
溶解性 | Soluble in 1N HCl (50 mg/ml), and water (slightly). |
密度 | 1.3330 |
应用 | An inhibitor of ischemic glutamate release |
产品介绍 | L-α-Aminoadipic acid, a gliotoxic analogue of glutamate, has been shown to competitively inhibit the transport protein of D-[3H]-aspartate. Experiments have reported that this compound also causes a reduction in ischemic glutamate release in murine hippocampal slices in vitro. Additional research suggests that L-α-Aminoadipic acid inhibits astrocyte culture Kynurenic acid synthesis which demonstrates the ability to modulate neuronal degeneration. L-α-Aminoadipic acid is a inhibitor of GluR and Gl Syn. |
别名 | L-2-氨基己二酸;(S)-2-氨基己二酸;Aad;L-2-Aminoadipic acid;(S)-2-Aminohexanedioic acid;L-Homoglutamic acid;H-2-Aad-OH;Aad |