![7,12-二甲基苯并[a]蒽](http://i3.antpedia.com/cbook/attachments/product/6751/D113432.gif!w580x440.jpg)
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产品描述
| 熔点 | 122-125°C |
| 溶解性 | Solubility in Toluene almost transparency |
| 存贮条件 | 储存温度2-8℃; 充氩保存 |
| 密度 | 0.9000 |
| 应用 | DMBA被p450酶氧化产生的代谢物能和DNA共价形成加合物，形成脱嘌呤碱基位点。 常用于在动物身上诱导皮肤和乳房瘤，也能诱发白血病和其它瘤。 |
| 产品介绍 | 7,12-Dimethylbenz[a]anthracene is a polycyclic aromatic hydrocarbon. It is used in cancer research. It is a carcinogenic organic pollutant generated from the incomplete combustion of gasoline and coal. |
| 生化机理 | The oxidation of DMBA by P450 enzymes produces metabolites that form covalent adducts with DNA and the formation within DNA of depurinated abasic sites. It is most commonly used to induce skin or mammary tumors in animals, though it also can induce leukemias and tumors at other sites. |
| 别名 | 7,12-二甲基苯并[a]蒽 ;7,12-二甲基苯蒽;DMBA;N,N-二甲基苄胺;N-苄基二甲胺;9,10-二甲基-1,2-苯并蒽;1,4-二甲基-2,3-苯并菲;1,4-Dimethyl-2,3-benzophenanthrene; 9,10-Dimethyl-1,2-benzanthracene; DMBA |
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