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产品描述
| 熔点 | 271-272°C |
| 存贮条件 | 储存温度2-8°C |
| 密度 | 1.3900 |
| 应用 | 对几个肿瘤细胞系具有抗增殖、抗凋亡活性，并抑制氧化偶氮甲烷（azoxymethane）诱发的大鼠结肠癌。依靠抑制HIV - 1蛋白酶活性，抑制HIV - 1病毒在单核细胞，巨噬细胞和单核细胞的复制， |
| 产品介绍 | 柠檬苦素是一种三萜苷元(triterpenoid aglycone),来自于柑桔类水果. |
| 生化机理 |
Limonin is a triterpenoid aglycone that is a bitter principle of citrus fruits. Limonin is chemically induced carcinogenesis inhibitor and HIV-1 replication inhibitor. Limonin has anti-proliferative, proapoptotic activity on several cancer cell lines and inhibits azoxymethane-induced colon cancer in rats. Limonin also inhibits HIV-1 replication in culturedf monocytes, macrophages, and mononuclear cells, perhaps by inhibition of HIV-1 protease activity. |
| 别名 | 吴茱萸内酯;柠檬苦素;Limonin Limonoic acid 3,19:16,17 dilactone |
