熔点 | 181°C-183°C |
存贮条件 | 储存温度2-8℃ |
产品介绍 | Vinorelbine ditartrate is a selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. This compound has been shown to inhibit the proliferation of multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells). |
生化机理 | Vinorelbine is a potent anti-mitotic, anti-tumor agent. Vinorelbine inhibits microtubule assembly. Low neurotoxicity is related to its higher affinity for mitotic microtubules than for axonal microtubules. |
别名 | 长春瑞宾双酒石酸盐;3′,4′-Didehydro-4′-deoxy-C′-norvincaleukoblastine [R-?(R*,R*)?-?2-?3-?dihydroxybutanedioate (1:2)salt], 5′-Noranhydrovinoblastine tartrate, KW-2307, NVB, Navelbine tartrate |