熔点 | 132 °C |
旋光率 | -10 to -18° (c=1, MeOH) |
敏感性 | 对热敏感 |
溶解性 | DMSO: >12 mg/mL at warmed to 60 °C;slightly soluble in water |
存贮条件 | 储存温度 -20 °C |
应用 | Tirofiban hydrochloride monohydrate has been used as an αIIbβ3 integrin (glycoprotein IIb/IIIa) inhibitor for mouse induced pluripotent stem cell (iPSC) culture. |
生化机理 | Tirofiban hydrochloride is a potent non-peptide, glycoprotein IIb/IIIa inhibitor. Blocks platelet aggregation and thrombus formation. Tirofiban might cause thrombocytopenia. |
别名 | 盐酸替罗非班 一水合物,N-(丁基磺酰基)-O-[4-(4-哌啶基)丁基]-L-酪氨酸盐酸盐 一水合物 ;N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine Hydrochloride Monohydrate; L 700462; MK 383 |