产品描述
| 熔点 | 149-152°C |
| 敏感性 | 对空气和热敏感 |
| 溶解性 | Soluble in ethanol, chloroform, and DMSO (100 mM). |
| 存贮条件 | 储存温度2-8°C，充氩保存 |
| 密度 | 1.2640 |
| 应用 |
原子吸收分析用试剂。发射光谱测定三价铬。多种金属络合剂。测尿中痕量铅。微量测定镉、钴、铋和钼。从酸性溶液中沉淀砷、铋、镉、钴、铜、铁、锰、镍、铅、锑、锡、钒、锌。 依托抑制NOS mRNA的翻译,从而防止一氧化氮合成酶(nitric oxide synthetase)的诱导;诱导大鼠血管平滑肌细胞凋亡和抑制白血病HL- 60细胞凋亡。99%规格适用于此类研究。 |
| 产品介绍 | 有氨气味。有吸湿性。在空气中不稳定，宜保存在氨气流中。微溶于乙醇。有刺激性。 |
| 生化机理 | Pyrrolidinedithiocarbamic acid (PDTC) ammonium salt is a potent inhibitor of NF κB (Nuclear Factor κB). Experiments show that micromolar amounts of this compound suppress IL-1β and completely inhibit the increase of nitric oxide synthase mRNA in response to IL-1β. Further studies suggest that PDTC ammonium salt also displays metal-ion chelating and antioxidant characteristics. |
| 别名 | 四亚甲基二硫代氨基甲酸铵;1-吡咯烷二硫代羧酸铵盐;吡咯烷二硫代氨基甲酸铵;APDC;PDC;PDTC;;Ammonium 1-pyrrolidinedithiocarbamate; APDC; PDC; PDTC; Pyrrolidinedithiocarbamate, ammonium derivative; Ammonium tetramethylenedithiocarbamate; Ammonium 1-Pyrrolidinecarbodithioate; 1-Pyrrolidinecarbodithioic Acid Ammonium Salt; Ammonium Pyrrolidine-N-dithiocarbamate; Pyrrolidine-N-dithiocarbamic Acid Ammonium Salt; |
