溶解性 | Soluble in water (100 mg/ml), DMSO (< 1 mg/ml), and ethanol (< 1 mg/ml). |
存贮条件 | 储存温度2-8℃ |
应用 | 生化研究,防止凝血酶原转变成凝血酶。 |
产品介绍 | 几乎无臭。无味。为一种天然多糖,取自猪或牛肠粘液或牛肺。有吸湿性。易溶于水(1g溶于20ml水),溶于盐水溶液,几乎不溶于乙醇、乙醚、丙酮、氯仿和苯。1%的水溶液pH为6.0-7.5。半数致死量(大鼠,静脉)354mg/kg。 |
生化机理 | Heparin, Sodium salt is a low molecular weight heparin (LMWH) polymer that produces its major anticoagulant effect by activating antithrombin. This activation causes a conformational change in ATIII and allows for increased flexibility in its reactive site loop. Heparin is a highly sulfated glycosaminoglycan known for preventing clots. Heparin, Sodium Salt is also an activator of RyR and ATIII. |
别名 | 肝磷脂;肝素;肝磷脂钠盐;Heparin sodium; Heparin; Deligoparin sodium; Minolteparin sodium; Nadroparine sodium |