产品描述
| 熔点 | 223-224°C |
| 敏感性 | 对热敏感 |
| 存贮条件 | 储存温度 2-8°C |
| 密度 | 1.5920 |
| 应用 | 泻药/泻剂化合物;内源性乙酰胆碱的释放增加了肠道平滑肌收缩。遗传毒性和致突变性似乎是由芦荟大黄素由于抑制拓扑异构酶II活性 |
| 产品介绍 | 易溶于热乙醇，在苯及乙醚中呈黄色，在氨水和硫酸中呈绯红色，属蒽醌类化合物，在酸性溶液中被还原则生成蒽酚及其互变异构体的蒽酮。 |
| 生化机理 | Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin. |
| 别名 | 1,8-二羟基-3-羟甲基蒽醌;芦荟泻素1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone;3-Hydroxymethylchrysazine |
