产品描述
| 存贮条件 | 储存温度-20°C |
| 备注 | 本产品只用于科研之用。 |
| 生化机理 | Synthetic vitamin D3 analog that is metabolized to 1,25-dihydroxycholecalcif?erol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells. Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol is a synthetic analog that is metabolized to 1,25-dihydroxycholecalcif?erol, the biologically active form of vitamin D3 in calcium absorption and deposition. 1α,25-Dihydroxyvitamin D3 has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function. Recent studies suggest that 1α,25-dihydroxyvitamin D3 acts as a chemopreventive agent against several malignancies including cancers of the prostate and colon and shows synergy with other anticancer compounds. |
| 别名 | ;1α-Hydroxycholecalciferol, Alfacalcidol 1α-Hydroxyvitamin D3 |
