产品描述
| 溶解性 | solubility DMSO: 10 mg/mL, clear;Ethanol :7 mg/mL Insoluble in water |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | IQ-1可以使小鼠胚胎干细胞在Wnt/β-catenin信号的驱使下扩增并阻止其非定向分化。在经Wnt3a处理的细胞中，维持维持胚胎干细胞(ESC)多能性、阻止PP2A/Nkd的相互作用。 |
| 生化机理 | IQ-1 enhances β-catenin/CBP interactions and blocks β-catenin/p300 driven transcription, which enables mouse embryonic stem cells (ESCs) to be maintained in an undifferentiated pluripotent state, allowing expansion and self-renewal of mouse ESC populations. |
| 别名 | ;2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide |
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