熔点 | 127-131℃ |
敏感性 | 对热敏感&对光线敏感 |
溶解性 | Soluble in ethyl acetate at 50mg/ml. Soluble in DMSO and ethanol. |
存贮条件 | 储存温度:-20℃ |
密度 | 1.2660 |
应用 | Caffeic acid phenethyl ester (CAPE) is the active component of propolis, a honeybee hive product. Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor, NF-κB.CAPE has been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation. Caffeic acid phenethyl ester inhibits HIV-1 integrase, and also inhibits proliferation of transformed cells. It induces apoptosis in transformed fibroblasts, and interferes with EGF signal transduction affecting both protein kinase C and ornithine decarboxylase activity. |
生化机理 | 咖啡酸苯乙酯是核转录因子 NF-κ B的特异性抑制剂。 |
别名 | 3,4-二羟基肉桂酸苯乙酯;CAPE;3,4-Dihydroxycinnamic Acid Phenethyl Ester;Phenethyl 3,4-Dihydroxycinnamate;Phenethyl Caffeate |