产品描述
| 敏感性 | 对光线、空气敏感 |
| 溶解性 | Insoluble in water. Soluble to 25 mM in ethanol with gentle warming and to 100 mM in DMSO. |
| 存贮条件 | 充氩保存 |
| 应用 |
6-Nitroveratraldehyde has been used in the preparation of: · no-carrier-added 6-18F-fluoro-L-dopa, fundamental tracer for cerebral positron emission tomography studies of dopaminergic system in humans · o-nitroaryl-bis(5-methylfur-2-yl)methanes, versatile synthons for the synthesis of nitrogen-containing heterocycles |
| 产品介绍 | DMNB (4,5-dimethoxy-2-nitrobenzaldehyde) is a cell-permeable vanillin derivative and potent inhibitor of DNA-PK (IC50 = 15 μM). DMNB is shown in experiments to increase DR4/DR5 mRNA levels and their surface expression and decrease c-FLIP mRNA levels in K56. DMNB is also an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair. |
| 别名 | 3,4-二甲氧基-6-硝基苯甲醛;;3,4-Dimethoxy-6-nitrobenzaldehyde;4,5-Dimethoxy-2-nitrobenzaldehyde |
