硅烷-PEG-丙烯酸酯

硅烷-PEG-丙烯酸酯

产品参数

货号 规格 操作
S164284-100mg 咨询
S164284-500mg 咨询
更多货号咨询>>
关闭

服务地域:全国

属性:产地:上海; 品牌:阿拉丁 ;货期:现货

上海阿拉丁生化科技股份有限公司

高级会员 高级会员
推荐产品推荐产品
产品描述产品描述

属性

溶解性 Off-white/white solid or viscous liquid depends on molecule weight;Soluble in regular aqeous solution as well as most organic solvents;
存贮条件 储存温度-20°C

描述

产品介绍 Ethoxy or methoxyl silane functionalized polyethylene glycol, silane PEG (PEG-Si) is a surface reactive PEG derivative that can be used to modify glass, silica and other surfaces via the reaction between hydroxyl group and ethoxyl/methoxyl silane. Pegylation can greatly suppress the non-specific binding of charged molecules to the modified surfaces. And they have wide applications for medica device, biomems or biocompatible material development.
生化机理

Generally, silane PEG is first dissolved in a mixture of ethanol/water solution, then allow the solution to contact with oxidized glass or silica surface for 30 min to 2 hours. Under this condition, silane PEG should bind to the material covalently.

Materials Required:

  • Pegylation solution: Ethanol/water (w/w, 95%/5%);
  • Silane PEG stock solution, 10~50 mg/mL in pegylation solution, prepare in fresh.
  • Washing solution: Distilled water.

Reaction Steps:

1. Dissolve targeted materials in Pegylation buffer.

2. Add silane PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of silane PEG needed for optimal conjugation;

3. Allow mixture agitates at room temperature for 30 min at room temperature or 2 hours at 4 -20 0C.

4. Wash out unreacted materials either by distilled water.

别名 ;
AI问答 配套的仪器设备? X
店铺 店铺 咨询留言 咨询留言 热线电话 热线电话