溶解性 | Off-white/white solid or viscous liquid depends on molecule weight;Soluble in regular aqeous solution as well as most organic solvents; |
存贮条件 | 储存温度-20°C |
产品介绍 | Ethoxy or methoxyl silane functionalized polyethylene glycol, silane PEG (PEG-Si) is a surface reactive PEG derivative that can be used to modify glass, silica and other surfaces via the reaction between hydroxyl group and ethoxyl/methoxyl silane. Pegylation can greatly suppress the non-specific binding of charged molecules to the modified surfaces. And they have wide applications for medica device, biomems or biocompatible material development. |
生化机理 |
Generally, silane PEG is first dissolved in a mixture of ethanol/water solution, then allow the solution to contact with oxidized glass or silica surface for 30 min to 2 hours. Under this condition, silane PEG should bind to the material covalently. Materials Required:
Reaction Steps: 1. Dissolve targeted materials in Pegylation buffer. 2. Add silane PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of silane PEG needed for optimal conjugation; 3. Allow mixture agitates at room temperature for 30 min at room temperature or 2 hours at 4 -20 0C. 4. Wash out unreacted materials either by distilled water. |
别名 | ; |