熔点 | 234-238°C |
敏感性 | 对光线敏感 |
溶解性 | 3,3′,5-Triiodo-L-thyronine dissolves in 4M NH4OH in MeOH at 5 mg/ml to yield a colorless to light yellow, clear to very slightly hazy solution. |
存贮条件 | 储存温度-20℃ |
应用 | 3,3′,5-Triiodo-L-thyronine can be used for Insulin-like growth factor I assays performed by using a double antibody radioimmunoassay. The product can also be used for in vitro transfection of 293T cells. |
产品介绍 | 3,3',5-Triiodo-L-thyronine是由前甲状腺素(T4)脱碘生成的甲状腺素,是甲状腺素受体TRα/TRβ的激动剂 |
生化机理 | 3,3′,5-Triiodo-L-thyronine also referred to as O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine or T3 is the biologically active thyroid hormone. In hypothyroidism pateints, triiodothyronine enhances mood and neuropsychological function. The product also positively regulates the hepatic FGF21 expression and stimulates the metabolic breakdown of glucose, fats, and proteins by enhancing the levels of numerous metabolic enzymes such as hexokinase, liver glucose 6-phosphatase as well as mitochondrial enzymes for oxidative phosphorylation. Additionally, the product facilitates the normal body growth in children and is pivotal for central nervous system maturation in foetus |
别名 | O-(4-羟基-3-碘苯基)-3,5-二碘代-L-酪氨酸; T3 碘噻罗宁;O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine;HY-A0070A; L-3,3',5-Triiodothyronine; Liothyronine; Tresitope |