产品描述
| 熔点 | 257°C |
| 溶解性 | Soluble in 0.1N HCl (moderately), and water (5 mM). |
| 应用 | NO合成酶抑制剂 |
| 产品介绍 | Nω-Nitro-L-arginine displays potent inhibition of NOS with selectivity for NOS1 and NOS3 over NOS2. It has been observed to inhibit endothelial nitric oxide biosynthesis and decrease radical generation of peroxynitrite ions. Other inhibitory effects demonstrated in experiments include blocking brady-kinin-induced relaxation in dog coronary artery strips and suppressing morphine tolerance in mice. N G-Nitro-L-arginine causes significant vasoconstriction and is utilized in studying nitric oxide as a neuronal messenger. |
| 别名 | L-NNA;Nω-硝基-L-精氨酸;L-NNA;H-Arg(NO2)-OH;NG-NO2-L-Arg;N5-(Nitroamidino)-L-2,5-diaminopentanoic acid |
