产品描述
| 存贮条件 | 储存温度-20°C |
| 应用 |
酪氨酸羟化酶(Tyrosine hydroxylase) 抑制剂。 α-Methyl-L-tyrosine is used to determine whether Fe2/ methamphetamine (METH) -induced cell death is dependent on cytosolic dopamine and iron mediated oxidative stress |
| 产品介绍 | 活性异构体 |
| 生化机理 | α-Methyl-L-tyrosine (L-AMPT) acts as a competitive inhibitor of tyrosine hydroxylase and inhibits the conversion of tyrosine to L-DOPA and eventually lowers dopamine synthesis in cytosol. AMPT at low concentrations can be used as a potent therapeutic for refractory dystonia or dyskinesia. It also helps in decreasing catecholamine concentration in pheochromocytoma patients |
| 别名 | 甲酪氨酸;L-alpha-甲基酪氨酸;酚丁氨酸;(S)-α-甲基酪氨酸;L-AMPT;L-2-Me-Tyr-OH ;L-α-Methylrosine;(S)-alpha-Methyltyrosine ;(S)-alpha-Methyl-4-hydroxyphenylalanine ;L-2-Methyl-3-(4-hydroxy-phenyl)alanine,L-2-Methyl-3-(4-hydroxy-phenyl)alanine |
