产品描述
| 应用 | A calcium channel protein inhibitor. |
| 产品介绍 | Dantrolene is a small molecule inhibitor of the Ryanodine receptor and a calcium channel protein inhibitor.Blockade of Ca2+ release from the sarcoendoplasmic reticulum, strongly related to excitation and contraction of muscles, generates a muscle relaxant effect correlated with Dantrolene. The neurotoxicity presented by pronounced glutamate activity is correlated to excessive rises in cytoplasmic Ca2+ levels, and Dantrolene is accordingly indicated as a neuroprotective agent against neurotrasmitter-induced excitotoxicity. Dantrolene, Sodium Salt is an inhibitor of RyR-1 and RyR-3. |
| 生化机理 | 肌浆网 Ca2+ 释放的抑制剂；肌肉松弛剂。 |
| 别名 | 1-[[[5-(4-硝基苯)-2-呋喃基]亚甲基氨基]-2,4-咪唑啉二酮 钠盐;丹曲林钠;1-[[[5-(4-硝基苯)-2-呋喃亚甲基]氨基]-2,4-咪唑烷二酮钠盐;1-[(5--(p-Nitro-phenyl)-fur-furyl-idene)-amino]-hydan-toin sodium salt;1-[5-(-4-Nitrophenyl)furfurylideneamino]imidazolidine-2,4-dione sodium |
