产品描述
| 沸点 | 280°C |
| 熔点 | 145°C |
| 敏感性 | 对空气敏感 |
| 溶解性 | Soluble in DMSO (23 mg/ml at 25 °C), ethanol (23 mg/ml at 25 °C), chloroform (~222.22 mg/ml), water (~200 mg/ml), and methanol. |
| 存贮条件 | 充氩保存 |
| 密度 | 1.2800 |
| 应用 | 用于甲亢原料药。 |
| 产品介绍 | A JAK/STAT signaling pathway inhibitor |
| 生化机理 | Methimazole is an antithyroid compound found to have antioxidant properties. Methimazole inhibits activation of the IFN-g-induced Janus kinase (JAK)/STAT signaling pathway in FRTL-5 thyroid cells, which may account for its immunodolulatory effects. Additionally, methimazole is an inhibitor of thyroperoxidase. |
| 别名 | 甲巯咪唑;1-甲基咪唑-2-硫醇;甲硫咪唑;1-Methyl-2-imidazolethiol; Methimazole; 1-Methylimidazole-2-thiol; Thiamazole; 2H-Imidazole-2-thione; 1,3-Dihydro-1-methyl-2H-imidazole-2-thione |
