产品描述
| 敏感性 | 对热及光敏感 |
| 溶解性 | DMSO : ≥ 4.1 mg/mL |
| 存贮条件 | 贮存温度2-8°C |
| 应用 | 它是一个经典的抗精神病药物，能够抑制 5-HT2A 受体，α1A 肾上腺素能受体，多巴胺D2/D3、D2L 受体, 以及 组胺H1 受体，对应的 Ki 值分别为5.6，10，0.765/0.13，3.4 和8 nM。 |
| 产品介绍 | Perphenazine is an antipsychotic drug used in treating schizophrenia. It modulates antioxidant levels and helps in the management of oxidative injury in schizophrenia. However, it is less effective than the clozapine drug group in improving response to oxidative injury. |
| 生化机理 | D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. |
| 别名 | 奋乃静;4-[3-(2-氯吩噻嗪-10-基)丙基]-1-哌嗪乙醇;2-氯-10-[3-[4-(2-羟基乙基)哌嗪-1-基]丙基]吩噻嗪 ;4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol;2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine;4-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-piperazineethanol |
